Strain Differences in the Behavioral Effects of Antidepressant Drugs in the Rat Forced Swimming Test
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چکیده
منابع مشابه
Antidepressant behavioral effects of duloxetine and fluoxetine in the rat forced swimming test.
PURPOSE To compare the effects of the antidepressant drugs duloxetine and fluoxetine on depressive behaviors in rodents. METHODS Eighteen male Wistar rats were given systemic injections of duloxetine, fluoxetine, or saline prior to a Forced Swimming Test (FST). Immobility and number of stops were measured. RESULTS Rats given injections of fluoxetine displayed significantly less immobility (...
متن کاملAntidepressant behavioral effects of duloxetine and amitriptyline in the rat forced swimming test.
PURPOSE To compare the effects of the antidepressant drugs duloxetine and amitriptyline on depressive behaviors in rats. METHODS Fifteen male Wistar rats were given systemic injections of duloxetine, amitriptyline or saline prior to a Forced Swimming Test (FST). Immobility and number of stops were measured. Data were analyzed by one-way ANOVA and Kruskall-Wallis. RESULTS Rats given injectio...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2000
ISSN: 0893-133X
DOI: 10.1016/s0893-133x(99)00100-1